Understanding HRD and its Role in Cancer Detection: A Guide for Genomic Testing Companies
Homologous Recombination Deficiency (HRD) refers to a condition where a cell's ability to repair DNA double-strand breaks via the homologous recombination repair (HRR) pathway is compromised. This deficiency can lead to genomic instability, a hallmark of many cancer types.
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Optimizing Cancer Genomic Testing with HRD Reference Standards: A Focus on Precision and Quality
In the field of cancer genomics research, ensuring accurate and reproducible results is critical for the development and validation of high-performance assays. As genomic technologies such as Next-Generation Sequencing (NGS) continue to evolve, the demand for reliable and standardized reference materials has grown.
More >> Is It Better To Be HRD Positive or Negative?
You may hear your doctor say HRD positive or HRD negative when talking about cancer. HRD positive means your cells cannot fix DNA damage well. HRD negative means your cells fix DNA damage easily. About half of patients are in each group:Knowing your HRD status helps doctors choose your treatment.
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