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STR Reference Standard
Description
In STR experiments, how to judge the accuracy of the results is essential. Standards are indispensable. CB-Gene now launches STR-related standards, which mainly include 1. Cell identification: autosomal series and sex chromosome series, as well as species contamination. 2. Reproductive inheritance: chromosome aneuploidy pairing standards (mother and fetus) and maternal cell contamination detection standards.
Introduction
 Human Autosomal STR standards Autosomal series, divided into two standards for males (9948) and females (9947): Contains 20 commonly used STR loci (including 13 CODIS loci) and one sex locus Amelogenin. |
Human Sex Chromosome STR standards The X chromosome standard contains 19 X-STR loci and one gender locus, Amelogenin. The Y chromosome standard contains 22 low-frequency mutation Y-STR loci and 7 high-frequency mutation Y-STR loci. | |
Human Contamination Detection STR standards STR testing utilizes the polymorphism of short tandem repeat sequences in DNA molecules. These sequences consist of 2-6 bases forming a core sequence that is repeated in tandem, and the length polymorphism is generated by the change in the number of core sequence repeats. This polymorphism can be used to distinguish different individuals. | Species Contamination Identification STR standards STR testing exploits the polymorphism of short tandem repeats found in DNA molecules. These sequences consist of a core sequence of 2-6 bases, which are repeated in tandem. Variations in the number of repeats create length polymorphisms. This polymorphism can be used to distinguish between individuals. STR identification results can confirm the following: 1. Whether the cells are of human origin; 2. Whether they are a standard cell line; and 3. Whether there is any cross-species contamination. | |
Species Identification STR testing exploits the polymorphism of short tandem repeats found in DNA molecules. These sequences consist of a core sequence of 2-6 bases, which are repeated in tandem. Variations in the number of repeats create length polymorphisms. This polymorphism can be used to distinguish between individuals. STR identification results can confirm the following: 1. Whether the cells are of human origin; 2. Whether they are a standard cell line; and 3. Whether there is any cross-species contamination. |
