Mutation

Introduction

Gene mutation refers to sudden and permanent alterations in cellular genetic material (typically DNA within the cell nucleus). This encompasses point mutations caused by single-base changes, as well as deletions, duplications, and insertions involving multiple bases. Causes may include errors in genetic replication during cell division, or exposure to chemicals, mutagens, radiation, and viruses. Mutations often disrupt normal cellular function, may lead to cell death, and in multicellular organisms, can contribute to diseases such as cancer.

We have established mutation reference standards for routine quality control and performance validation. These could ensure high specificity and repeatability, thereby enhancing detection.

Preparation Process

Key Features

• Cell-line–derived reference materials that closely mimic patient samples

• Compatible with multiple testing platforms for comprehensive performance evaluation

• High efficiency, reducing customer purchasing cycles and experimental time

• High accuracy and sensitivity to improve the reliability of test results

• Multiple gene loci included, covering a wide range of relevant target genes

• Strict QC procedures to ensure stable and consistent product quality