SNV standards refer to genomic DNA extracted from cells, rigorously quality-controlled, and standardized with known concentration, sequence information, and specific genetic variant characteristics. They are commonly used to calibrate experimental systems, validate the accuracy of assays, evaluate the performance of sequencing or PCR technologies, and serve as positive controls or quantitative references. Unlike standard SNVs, standards must possess high purity, integrity, and stability, and their genetic background and variant information must be fully verified.

1. Addressing Complex Research Needs: Many studies involve specific gene mutations, rare variants, or complex genomic structures (such as fusion genes and copy number variations). Universal standards cannot address these individual scenarios. Customized standards precisely match the target sequence, ensuring targeted experimental results.

2. Improving Test Accuracy and Reliability: In molecular diagnostics, customized SNV standards can mimic the genetic profile of clinical samples and are used to validate the sensitivity, specificity, and reproducibility of assays. For example, tumor genetic testing requires standards containing specific mutation sites to monitor the risk of false negatives.

3. Standardized experimental procedures: Data comparability across different laboratories or platforms requires consistent standards. Customized standards allow users to unify reference systems, reduce batch-to-batch variability, and improve the efficiency of multi-center research collaboration.

4.Circumventing ethical and sample acquisition challenges: Certain rare mutations or pathogen DNA are difficult to obtain from natural samples. Custom synthesis can avoid ethical restrictions and provide a safe and stable alternative.

• Samples are derived from human cell lines, maximizing the similarity to patient samples.
• Suitable for performance evaluation across multiple platforms.
• Highly accurate and sensitive, ensuring accurate test results.
• High efficiency, reducing customer procurement cycles and experimental time.
• Products cover multiple loci and various relevant genes.
• Strict quality control ensures consistent quality.