HLA Reference Standard

Human leukocyte antigen (HLA) is an important part of the human immune system and is also the most complex genetic polymorphism system known to the human body. 

According to its structure, tissue distribution and function, HLA molecules can be divided into three types: HLA-I, HLA-II and HLA-III. 

Among them, the functions of HLA-I and HLA-II molecules are mainly related to immune rejection, and the functions of HLA-III molecules are mainly related to the synthesis of some immune-related complement systems and inflammatory-related factors. 

Clinical transplantation studies have found that the long-term survival rate of the graft is positively correlated with the matching degree of HLA-I and HLA-II molecules between the donor and the recipient. The higher the matching degree of HLA molecules between the donor and the recipient, the higher the long-term survival rate of the graft.

Single HLA locus genotyping Covers relevant sites for common autoimmune disease drugs such as HLA-B*27:04 HLA-B*58:01 HLA-B*57:01 HLA-B*15:02.   More>

HLA matching multi-locus genotyping Containing more than 11 alleles, accurate HLA high-resolution typing and matching can reduce graft-versus-host disease (GVHD) and improve the success rate of transplantation.   More>