Translocation Reference Standard

Background

Translocation refers to the translocation of sequences within or between chromosomes.

It is a key biomarker for the diagnosis of hematological malignancies, genetic diseases and infertility. To ensure the accuracy and reproducibility of clinical testing and research,Our translocation Standard References are meticulously designed to simulate common pathological breakpoints (e.g.,ABL1-BCR, FGFR2-BICC1) and provide reliable controls for fluorescence in situ hybridization (FISH), PCR, and next-generation sequencing (NGS) platforms.

Key Features

• High Specificity & Precision :Validated genomic sequences covering breakpoint regions with ±1% accuracy, ensuring minimal cross-reactivity.

• Multi-Platform Compatibility :Optimized for FISH probes, qPCR assays, and NGS workflows, enabling seamless integration into existing diagnostic pipelines.

• Comprehensive QC Metrics :Batch-to-batch consistency verified by dual Sanger sequencing and digital droplet PCR (ddPCR).

Applications

• Clinical Oncology: Test the sensitivity, specificity and stability of fusion gene detection to assist in the development of clinical test kits.

• Research: Study chromosomal instability mechanisms or validate novel translocation detection assays.