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CBPE0306-0319
CBPE0306-0319
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Product Description
SDC2 (Syndecan-2) is a gene encoding a transmembrane heparan sulfate proteoglycan that plays an important role in cell adhesion, migration, and proliferation. Recent studies have shown that aberrant methylation of the SDC2 gene is closely associated with the development and progression of colorectal cancer (CRC). The SDC2 gene promoter region is typically hypomethylated in normal tissues, but in the early stages of CRC, it often becomes hypermethylated, leading to gene silencing and loss of function.
Based on this mechanism, SDC2 methylation has become an important biomarker for noninvasive early screening of CRC. Measuring SDC2 methylation levels in stool or blood allows for noninvasive cancer risk assessment.
SDC2 methylation standards are reference materials designed to ensure the accuracy and comparability of test results. These standards typically contain fully methylated and unmethylated SDC2 gene fragments and are used to establish standard curves, validate the sensitivity and specificity of assays, and assist laboratories in quality control and standardization. It holds significant value in clinical diagnosis, molecular detection kit development, and scientific research, helping to promote the standardized application of early colorectal cancer screening technology.
In summary, the SDC2 methylation standard is a key tool supporting the quality system of molecular diagnostics, providing a reliable technical foundation for early cancer screening based on methylation markers.
The SDC2 methylation standard launched by Kebai Gene ensures the detection limit, sensitivity, and stability of the diagnostic method, and facilitates the development of methylation detection kits for early cancer screening.
General information
| Name | SDC2 methylation single gene single segment standard |
| Cat. No. | CBPE0306-0319 |
| Format | Genomic DNA |
| Size | 1ug |
| Buffer | Tris-EDTA |
| Intended Use | Research Use Only |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Storage Conditions | 2~8℃ |
| Expiry | 36 months from the date of manufacture |
| Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. |
Technical Data
| Classification | Cat No. | Name | Unit Size | Methylation level | |
| Chr8:97506250-97506398(hg19) | |||||
| quality control standard | Positive quality control | CBPE0306 | SDC2 Methylation Positive control | 1ug | 99.79% |
| Negative quality control | CBPE0307 | SDC2 Methylation Negative control (< Cut off) | 1ug | 0.00% | |
| Reference Standard | High positive reference-1 | CBPE0308 | SDC2 Methylation Reference Standard with > 90% | 1ug | 99.79% |
| High positive reference-2 | CBPE0309 | SDC2 Methylation Reference Standard with 10% | 1ug | 9.55% | |
| Low positive reference | CBPE0310 | SDC2 Methylation Reference Standard with 3% | 1ug | N/A | |
| LOD reference | CBPE0311 | SDC2 Methylation Reference Standard with 1% | 1ug | 1.27% | |
| Negative reference | CBPE0312 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |
| Precision reference | CBPE0310 | SDC2 Methylation Reference Standard with 3% | 1ug | N/A | |
| CBPE0312 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
| Specificity reference | Customization | ||||
| Remark | 1. Quality control products are also called accuracy standards, which are used for qualitative judgment; 2. Reference products are used for qualitative and quantitative judgments, among which the judgment of strong positive, weak positive, detection limit, precision, and specificity depends on the specific project. The judgment of this product is only an internal standard; 3. Quality control products are used for performance evaluation, factory inspection, and routine testing and judgment of test kits, and reference products are used for performance evaluation and factory inspection; | ||||
| Classification | Cat No. | Name | Unit Size | Methylation level | |
| Chr8:97506434-97506502(hg19) | |||||
| quality control standard | Positive quality control | CBPE0313 | SDC2 Methylation Positive control | 1ug | 91.70% |
| Negative quality control | CBPE0314 | SDC2 Methylation Negative control (< Cut off) | 1ug | 0.22% | |
| Reference Standard | High positive reference-1 | CBPE0315 | SDC2 Methylation Reference Standard with > 90% | 1ug | 91.70% |
| High positive reference-2 | CBPE0316 | SDC2 Methylation Reference Standard with 10% | 1ug | 14.82% | |
| Low positive reference | CBPE0317 | SDC2 Methylation Reference Standard with 3% | 1ug | 3.66% | |
| LOB limit reference | CBPE0318 | SDC2 Methylation Reference Standard with 1% | 1ug | 1.54% | |
| Negative reference | CBPE0319 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.22% | |
| Precision reference | CBPE0317 | SDC2 Methylation Reference Standard with 3% | 1ug | 3.66% | |
| CBPE0319 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.22% | ||
| Specificity reference | Customization | ||||
| Remark | 1. Quality control products are also called accuracy standards, which are used for qualitative judgment; 2. Reference products are used for qualitative and quantitative judgments, among which the judgment of strong positive, weak positive, detection limit, precision, and specificity depends on the specific project. The judgment of this product is only an internal standard; 3. Quality control products are used for performance evaluation, factory inspection, and routine testing and judgment of test kits, and reference products are used for performance evaluation and factory inspection; | ||||
Product Description
SDC2 (Syndecan-2) is a gene encoding a transmembrane heparan sulfate proteoglycan that plays an important role in cell adhesion, migration, and proliferation. Recent studies have shown that aberrant methylation of the SDC2 gene is closely associated with the development and progression of colorectal cancer (CRC). The SDC2 gene promoter region is typically hypomethylated in normal tissues, but in the early stages of CRC, it often becomes hypermethylated, leading to gene silencing and loss of function.
Based on this mechanism, SDC2 methylation has become an important biomarker for noninvasive early screening of CRC. Measuring SDC2 methylation levels in stool or blood allows for noninvasive cancer risk assessment.
SDC2 methylation standards are reference materials designed to ensure the accuracy and comparability of test results. These standards typically contain fully methylated and unmethylated SDC2 gene fragments and are used to establish standard curves, validate the sensitivity and specificity of assays, and assist laboratories in quality control and standardization. It holds significant value in clinical diagnosis, molecular detection kit development, and scientific research, helping to promote the standardized application of early colorectal cancer screening technology.
In summary, the SDC2 methylation standard is a key tool supporting the quality system of molecular diagnostics, providing a reliable technical foundation for early cancer screening based on methylation markers.
The SDC2 methylation standard launched by Kebai Gene ensures the detection limit, sensitivity, and stability of the diagnostic method, and facilitates the development of methylation detection kits for early cancer screening.
General information
| Name | SDC2 methylation single gene single segment standard |
| Cat. No. | CBPE0306-0319 |
| Format | Genomic DNA |
| Size | 1ug |
| Buffer | Tris-EDTA |
| Intended Use | Research Use Only |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Storage Conditions | 2~8℃ |
| Expiry | 36 months from the date of manufacture |
| Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. |
Technical Data
| Classification | Cat No. | Name | Unit Size | Methylation level | |
| Chr8:97506250-97506398(hg19) | |||||
| quality control standard | Positive quality control | CBPE0306 | SDC2 Methylation Positive control | 1ug | 99.79% |
| Negative quality control | CBPE0307 | SDC2 Methylation Negative control (< Cut off) | 1ug | 0.00% | |
| Reference Standard | High positive reference-1 | CBPE0308 | SDC2 Methylation Reference Standard with > 90% | 1ug | 99.79% |
| High positive reference-2 | CBPE0309 | SDC2 Methylation Reference Standard with 10% | 1ug | 9.55% | |
| Low positive reference | CBPE0310 | SDC2 Methylation Reference Standard with 3% | 1ug | N/A | |
| LOD reference | CBPE0311 | SDC2 Methylation Reference Standard with 1% | 1ug | 1.27% | |
| Negative reference | CBPE0312 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |
| Precision reference | CBPE0310 | SDC2 Methylation Reference Standard with 3% | 1ug | N/A | |
| CBPE0312 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
| Specificity reference | Customization | ||||
| Remark | 1. Quality control products are also called accuracy standards, which are used for qualitative judgment; 2. Reference products are used for qualitative and quantitative judgments, among which the judgment of strong positive, weak positive, detection limit, precision, and specificity depends on the specific project. The judgment of this product is only an internal standard; 3. Quality control products are used for performance evaluation, factory inspection, and routine testing and judgment of test kits, and reference products are used for performance evaluation and factory inspection; | ||||
| Classification | Cat No. | Name | Unit Size | Methylation level | |
| Chr8:97506434-97506502(hg19) | |||||
| quality control standard | Positive quality control | CBPE0313 | SDC2 Methylation Positive control | 1ug | 91.70% |
| Negative quality control | CBPE0314 | SDC2 Methylation Negative control (< Cut off) | 1ug | 0.22% | |
| Reference Standard | High positive reference-1 | CBPE0315 | SDC2 Methylation Reference Standard with > 90% | 1ug | 91.70% |
| High positive reference-2 | CBPE0316 | SDC2 Methylation Reference Standard with 10% | 1ug | 14.82% | |
| Low positive reference | CBPE0317 | SDC2 Methylation Reference Standard with 3% | 1ug | 3.66% | |
| LOB limit reference | CBPE0318 | SDC2 Methylation Reference Standard with 1% | 1ug | 1.54% | |
| Negative reference | CBPE0319 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.22% | |
| Precision reference | CBPE0317 | SDC2 Methylation Reference Standard with 3% | 1ug | 3.66% | |
| CBPE0319 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.22% | ||
| Specificity reference | Customization | ||||
| Remark | 1. Quality control products are also called accuracy standards, which are used for qualitative judgment; 2. Reference products are used for qualitative and quantitative judgments, among which the judgment of strong positive, weak positive, detection limit, precision, and specificity depends on the specific project. The judgment of this product is only an internal standard; 3. Quality control products are used for performance evaluation, factory inspection, and routine testing and judgment of test kits, and reference products are used for performance evaluation and factory inspection; | ||||
General information
Name | SDC2 methylation single gene single segment standard |
Cat. No. | CBPE0306-0319 |
Format | Genomic DNA |
Size | 1ug |
Buffer | Tris-EDTA |
Intended Use | Research Use Only |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Storage Conditions | 2~8℃ |
Expiry | 36 months from the date of manufacture |
Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. |
General information
Name | SDC2 methylation single gene single segment standard |
Cat. No. | CBPE0306-0319 |
Format | Genomic DNA |
Size | 1ug |
Buffer | Tris-EDTA |
Intended Use | Research Use Only |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Storage Conditions | 2~8℃ |
Expiry | 36 months from the date of manufacture |
Remark | The data in the instruction manual is the data of a single test, and the specific data of each batch is subject to delivery. |
Technical Data
Classification | Cat No. | Name | Unit Size | Methylation level | |
Chr8:97506250-97506398(hg19) | |||||
quality control standard | Positive quality control | CBPE0306 | SDC2 Methylation Positive control | 1ug | 99.79% |
Negative quality control | CBPE0307 | SDC2 Methylation Negative control (< Cut off) | 1ug | 0.00% | |
Reference Standard | High positive reference-1 | CBPE0308 | SDC2 Methylation Reference Standard with > 90% | 1ug | 99.79% |
High positive reference-2 | CBPE0309 | SDC2 Methylation Reference Standard with 10% | 1ug | 9.55% | |
Low positive reference | CBPE0310 | SDC2 Methylation Reference Standard with 3% | 1ug | N/A | |
LOB limit reference | CBPE0311 | SDC2 Methylation Reference Standard with 1% | 1ug | 1.27% | |
Negative reference | CBPE0312 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |
Precision reference | CBPE0310 | SDC2 Methylation Reference Standard with 3% | 1ug | N/A | |
CBPE0312 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
Specificity reference | Customization | ||||
Remark | 1. Quality control products are also called accuracy standards, which are used for qualitative judgment; 2. Reference products are used for qualitative and quantitative judgments, among which the judgment of strong positive, weak positive, detection limit, precision, and specificity depends on the specific project. The judgment of this product is only an internal standard; 3. Quality control products are used for performance evaluation, factory inspection, and routine testing and judgment of test kits, and reference products are used for performance evaluation and factory inspection; | ||||
Classification | Cat No. | Name | Unit Size | Methylation level | |
Chr8:97506434-97506502(hg19) | |||||
quality control standard | Positive quality control | CBPE0313 | SDC2 Methylation Positive control | 1ug | 91.70% |
Negative quality control | CBPE0314 | SDC2 Methylation Negative control (< Cut off) | 1ug | 0.22% | |
Reference Standard | High positive reference-1 | CBPE0315 | SDC2 Methylation Reference Standard with > 90% | 1ug | 91.70% |
High positive reference-2 | CBPE0316 | SDC2 Methylation Reference Standard with 10% | 1ug | 14.82% | |
Low positive reference | CBPE0317 | SDC2 Methylation Reference Standard with 3% | 1ug | 3.66% | |
LOD reference | CBPE0318 | SDC2 Methylation Reference Standard with 1% | 1ug | 1.54% | |
Negative reference | CBPE0319 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.22% | |
Precision reference | CBPE0317 | SDC2 Methylation Reference Standard with 3% | 1ug | 3.66% | |
CBPE0319 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.22% | ||
Specificity reference | Customization | ||||
Remark | 1. Quality control products are also called accuracy standards, which are used for qualitative judgment; 2. Reference products are used for qualitative and quantitative judgments, among which the judgment of strong positive, weak positive, detection limit, precision, and specificity depends on the specific project. The judgment of this product is only an internal standard; 3. Quality control products are used for performance evaluation, factory inspection, and routine testing and judgment of test kits, and reference products are used for performance evaluation and factory inspection; | ||||
Technical Data
Classification | Cat No. | Name | Unit Size | Methylation level | |
Chr8:97506250-97506398(hg19) | |||||
quality control standard | Positive quality control | CBPE0306 | SDC2 Methylation Positive control | 1ug | 99.79% |
Negative quality control | CBPE0307 | SDC2 Methylation Negative control (< Cut off) | 1ug | 0.00% | |
Reference Standard | High positive reference-1 | CBPE0308 | SDC2 Methylation Reference Standard with > 90% | 1ug | 99.79% |
High positive reference-2 | CBPE0309 | SDC2 Methylation Reference Standard with 10% | 1ug | 9.55% | |
Low positive reference | CBPE0310 | SDC2 Methylation Reference Standard with 3% | 1ug | N/A | |
LOB limit reference | CBPE0311 | SDC2 Methylation Reference Standard with 1% | 1ug | 1.27% | |
Negative reference | CBPE0312 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | |
Precision reference | CBPE0310 | SDC2 Methylation Reference Standard with 3% | 1ug | N/A | |
CBPE0312 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.00% | ||
Specificity reference | Customization | ||||
Remark | 1. Quality control products are also called accuracy standards, which are used for qualitative judgment; 2. Reference products are used for qualitative and quantitative judgments, among which the judgment of strong positive, weak positive, detection limit, precision, and specificity depends on the specific project. The judgment of this product is only an internal standard; 3. Quality control products are used for performance evaluation, factory inspection, and routine testing and judgment of test kits, and reference products are used for performance evaluation and factory inspection; | ||||
Classification | Cat No. | Name | Unit Size | Methylation level | |
Chr8:97506434-97506502(hg19) | |||||
quality control standard | Positive quality control | CBPE0313 | SDC2 Methylation Positive control | 1ug | 91.70% |
Negative quality control | CBPE0314 | SDC2 Methylation Negative control (< Cut off) | 1ug | 0.22% | |
Reference Standard | High positive reference-1 | CBPE0315 | SDC2 Methylation Reference Standard with > 90% | 1ug | 91.70% |
High positive reference-2 | CBPE0316 | SDC2 Methylation Reference Standard with 10% | 1ug | 14.82% | |
Low positive reference | CBPE0317 | SDC2 Methylation Reference Standard with 3% | 1ug | 3.66% | |
LOD reference | CBPE0318 | SDC2 Methylation Reference Standard with 1% | 1ug | 1.54% | |
Negative reference | CBPE0319 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.22% | |
Precision reference | CBPE0317 | SDC2 Methylation Reference Standard with 3% | 1ug | 3.66% | |
CBPE0319 | SDC2 Methylation Negative Reference Standard (< Cut off) | 1ug | 0.22% | ||
Specificity reference | Customization | ||||
Remark | 1. Quality control products are also called accuracy standards, which are used for qualitative judgment; 2. Reference products are used for qualitative and quantitative judgments, among which the judgment of strong positive, weak positive, detection limit, precision, and specificity depends on the specific project. The judgment of this product is only an internal standard; 3. Quality control products are used for performance evaluation, factory inspection, and routine testing and judgment of test kits, and reference products are used for performance evaluation and factory inspection; | ||||
